BIODATA
Address : Department of Biotechnology,
Joginpally BR Engineering College ,
Moinabad,
Hyderabad - 500075
http://www.jbrec.edu.in/biotech.php
( Formerly Professor & Head , Dept of Biochemistry,
Osmania University, Hyderabad -500007 )
e mail: guntupalli_v@lycos.com
Education : M.Sc ., Ph.D Biochemistry(Osmania University)
PROFESSIONAL AND RESEARCH EXPERIENCE
1966--1967 Research Fellow, Osmania Medical College, Hyderabad
1966--1967 Lecturer in Chemistry, SRAS College, Kothagudem,A.P.
1967---1969 Junior Scientific Assistant, (DAE Scheme ) Dept. Of Biochemistry, Osmania University, Hyderabad-500 007. A.P.
1970---1972 Junior Research Fellow (Dept. Of Atomic Energy), Dept. Of Biochemistry, Osmania University, Hyderabad-500 007. A.P
1973---1974 Senior Research Fellow (CSIR) Dept. Of Biochemistry, OsmaniaUniversity.
1974—1980 Lecturer in Biochemistry, Dept. Of Biochemistry, Osmania University, Hyderabad-500 007. A.P.
1981---1988 Reader, Dept. Of Biochemistry, Osmania University.
1989—2009 Professor of Biochemistry, Dept. Of Biochemistry, Osmania University.
1984---1986 Fogarty International post doctoral fellow of NIH, U.S.A Dept. Of Biology, New York University,New York
1987---1989 Visiting Research Scientist, Dept. Of Biology, New York University, New York, U.S.A.
1992---1992 Visiting Professor, Dept. Of Biology, New York University, New York.
1990---1992 Head, Dept. Of Biochemistry, Osmania University. Hyderabad - 500 007.
1992---1993 Chairman, Board of Studies in Biochemistry, Osmania University.
1993---1995 Head, Dept. Of Biochemistry, Osmania University, Osmania University.
1995 – 1997 Chairman , Board of Studies in Biochemistry Osmania University.
RESEARCH AREAS
Delta endotoxins and Proteases of Bacillus thuringiensis .
Molecular mechanisms of metal toxicities and resistance in fungi. Fungal Cell wall structure and their use as biosorbents. Applications of fungal chitin and its metal complexes
Fungal chitinases. Their application in fungal protoplast preparation and in biotechnology . Peptide antibiotics: Production , biosynthesis and their interaction with metals. Development of colored phenylisothiocyanates for protein end group analysis.
No. of Ph.Ds produced : Ten
CONSULATANT IN THE AREAS
2)Development of ELISA for the detection of Bt -toxin in Boll guard .,etc.
3)Fungal enzymes such as proteases ,chitinases ,glucanases from chrysosporium sp.
4)Probiotics
5)Production of Siderophores
AWARDS AND HONOURS
2)Consultant of many Biotech industries in A.P.
3)Attended several conferences . Delivered guest lectures , chaired scientific sessions , etc.
4)Scientific work cited in books and journals by many authors.
5)Resource person for SONET and participated in making video lessons for B.Tech , Biotechnology students of JNTU, on invitation.
6)Subject expert and member of several inspection committees and instrumental in initiating the teaching of Biochemistry and Biotechnology in various private institutions both at undergraduate and postgraduate level .
MEMBERSHIP & PRESTIGIOUS POSTS HELD
Member board of studies of several universities in subjects biochemistry, microbiology,
nutrition, etc.
Executive member, Academic Council , College of Science , Osmania University
Member , Committee for recognizing research supervisors , College of Science, Osmania University .
Member Faculty of Science, Kakatiya University, Warangal, A.P.
Examiner of several Universities at post graduation and doctoral level.
Organised several symposia and workshops in biochemistry and molecular biology.
BIOGRAPHY LISTED IN
1. Who'sWho in the World , by Marquis who's who , U.S.A.
2. American Biographical Institute , U.S.A.
3. International Biographical Centre , Cambridge , England.
4. Who is who in Asia
5. Member , Research Board of Advisors , The American Biographical Institute.
BOOKS
1. Fungal cell wall modifications and their use as biosorbents for metals.
Md.Naseem Akthar & G.VENKATESWERLU. 1994.
Microbes for better living, Micon International- 35:227-233.
2. Bacillus thuringiensis endoproteases : Newer avenues for research in the
production of insecticidal proteins .
G.VENKATESWERLU
In “ Molecular Mechanisms of Toxicity.” Pages 35 – 39, Ed.C.Subramanyam and
Surya S.Singh , Osmania University , Hyderabad , India . 1977.
3. Bacillus thuringiensis : Protioxins and the proteases.
Chandrahasa Y. Reddy , V.Rukmini and G.VENKATESWERLU.
In “ Microbials in Insect Pest Management.” Pages 31 –38
Eds. Ignacimuthu & A.Sen
Oxford and IBH Co.Pvt. Ltd. New Delhi , India. 2001.
4.Cloning of nitrate reductase gene (niaD) of Aspergillus niger and its use for
transformation of Beauveria bassiana .
J.R.Kinghorn , Shiela E. Unkles , S.S.Sandhu , R.C.Rajak &
G.VENKATESWERLU
In “ Biotechnology of Microbes and Sustainable Utilization “ Pages 128 –131
Ed. R.C.Rajak. 2002.
5.The insecticidal proteins of Bacillus thuringiensis and their activation by
proteases .
G.VENKATESWERLU , 2002.
In “Developments in Microbial Biochemistry and its impact on
Biotechnology “
P. 6 – 24.
Eds: B.Sashidhar Rao , P.Maruthi Mohan & C.Subramanyam,
Department of Biochemistry, Osmania University , Hyderabad.
6.Biotechnology of Mycoinsecticides for Microbial Control of Insect Pest .
Sardul Singh Sandhu , R.C.Rajak , and G.VENKATESWERLU . 2002.
In “ Developments in Microbial Biochemistry and its impact on
Biotechnology “.
P. 48 – 73.
Eds. B.Sashidhar Rao , P.Maruthi Mohan & C.Subramanyam,
Department of Biochemistry , Osmania University , Hyderabad .
LIST OF PUBLICATIONS
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1970.
Biochemical Journal ( U.K) , 118:497-503.
2. Interrelationships in trace elements metabolism in metal toxicities in a cobalt resistant strain of Neurospora crassa.
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1973.
Biochemical Journal (U.K) , 132: 673-680.
3. Effect of copper and manganese on free amino acid content of Neurospora crassa.
C.SUBRAMANYAM & G.VENKATESWERLU. 1979.
Neurospora Newsletter (U.S.A), 26:16.
4. The effect of copper on histidine biosynthesis in Neurospora crassa.
C.SUBRAMANYAM & G.VENKATESWERLU. 1979.
Journal of Biosciences, 1: 143-149.
5. Studies on copper toxicity in Neurospora crasassa.
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1979.
Indian Journal of Biochemistry & Biophysics, 16: 84-87.
6. Cobalt transport in a cobalt resistant strain of Neurospora crassa.
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1979.
Journal of Biosciences. 1: 433-439.
7. Some studies on histidine transport in Neurospora crassa.
C.SUBRAMANYAM & G.VENKATESWERLU. 1980.
Indian Journal of Experimental Biology, 18:1136-1138.
8. A modified nitroso-R salt procedure for determination of cobalt in presence of iron in biological samples.
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1981. .
Current Science, 50: 269.
9. Antifungal activity of Bacitracin and its interaction with metals.
G.VENKATESWERLU. 1981.
Journal of Biosciences, 3: 1-5.
10. A new repressible alkaline phosphatase in Neurospora crassa.
G.VENKATESWERLU & K.SIVARAMA SASTRY. 1982.Journal of Biosciences, 4: 275-279.
11. Copper interference in nitrite estimation by diazotization and its elimination.
C.SUBRAMANYAM & G.VENKATESWERLU. 1983.
Current Science, 53: 249-251.
12. Accumulation of histidinol phosphate in copper toxic cultures of Neurospora crassa.
C.SUBRAMANYAM , G.VENKATESWERLU. & S.L.N.RAO. 1983.
Current Science, 52: 879-880.
13.Cellwall composition of Neurospora crassa under conditions of copper toxicity. C.SUBRAMANYAM , G.VENKATESWERLU & S.L.N.RAO. 1983.
Applied & Environmental Microbiology (U.S.A), 46:585-590.
14. Nitrogen metabolism in the blue mycelia of Neurospora crassa isolated from copper toxic cultures.
SRINIVASA RAO, C.SUBRAMANYAM & G.VENKATESWERLU. 1984.
Current Microbiology (U.S.A), 10: 79-84.
15. A microbiological method for the estimation of histidine in proteins employing His- mutants of Neurospora crassa.
SRINIVASA RAO, C.SUBRAMANYAM & G.VENKATESWERLU. 1985.
Life Science Advances, 4: 5-6.
16. Glutamine metabolism in Neurospora crassa under conditions of copper toxicity.
SRINIVASA RAO & G.VENKATESWERLU. 1986.
Journal of Experimental Botany (U.K), 37: 947-955.
17. Copper and cobalt alter the cell wall composition of Cunninghamella blakesleeana.
G.VENKATESWERLU & G.STOTZKY. 1986.
Canadian Journal of Microbiology (Canada), 32: 654-662.
18. Metal ion influence on the growth inhibition of Neurospora crassa by bacitracin.
SRINIVASA RAO & G.VENKATESWERLU. 1989.
Current Microbiology (U.S.A) ,19: 253-258.
19. Morphological, ultra structural and chemical changes induced in Cunninghamella blakesleeana by copper and cobalt.
G.VENKATESWERLU, M.J.YODER & G.STOTZKY. 1989.
Applied Microbiology and Biotechnology ( Springer-Verlag International), 31: 204-210.
20. Binding of metals by cell walls of Cunninghamella blakesleeana grown in the presence of copper or cobalt.
G.VENKATESWERLU & G.STOTZKY. 1989.
Applied Microbiology and Biotechnology (Springer - Verlag International), 31: 619-625
8
21. Possible precursors for thiostrepton in Streptomyces azureus.
C.VASANT KUMAR CHARY, S.RAMBHAV, G.VENKATESWERLU &
L.K.RAMACHANDRAN. 1990.
Indian Journal of Microbiology, 28: 191-198
22. Inactivation of thiostrepton by copper (II) .
C.VASANT KUMAR CHARY , S.RAMBHAV & G.VENKATESWERLU. 1990.
Biology of Metals (Springer -Verlag International ) , 3: 48-53.
23. A simple method for the isolation of antilepidopteran toxin from Bacillus thuringiensis subsp. kurstaki.
G.VENKATESWERLU & G.STOTZKY. 1990.
Biotechnology & Applied Biochemistry (Academic Press, U.S.A), 12: 245-251.
24. Binding of protoxin and toxin proteins of Bacillus thuringiensis subsp. kurstaki on clay minerals.
G.VENKATESWERLU & G.STOTZKY. (1992) .
Current Microbiology (Springer-Verlag, N.Y.) , 25: 225-233.
25. Binding of insecticidal proteins of Bacillus thuringiensis on clay minerals.
G.STOTZKY,G.VENKATESWERLU , H.TAPP & J.KOSKELLA. 1992.
VIth International symposium on Microbial Ecology .
Barcelona, 6-11.
26. A rapid method for isolation of stable niaD and crnA mutants of entomopathogenic fungi Beauveria bassiana and Metarhizium anisopliae.
S.S.Sandhu & G.VENKATESWERLU. 1997.
Fungal Genetics Newsletter (U.S.A), 42:50-51.
27. Involvement of an endogenous metalloprotease in the activation of protection in Bacillus thuringiensis subsp.kurstaki.
N.Suresh Kumar & G.VENKATESWERLU. 1997.
Biochemistry & Molecular Biology International (U.S.A), 42:901-908.
28. Intracellular proteases in sporulated Bacillus thuringiensis subsp. tenebrionis: detection and analysis by gelatin zymography.
SREELATHA T.REDDY & G.VENKATESWERLU. 1997.
Biochemistry & Molecular Biology International (U.S.A), 43:935-943.
29. Endogenous protease activated 66kDa toxin from Bacillus thuringiensis subsp. kurstaki active against Spodoptera littoralis .
N.SURESH KUMAR, & G. VENKATESWERLU. 1998.
FEMS Microbiology Letters, (U.K), 159: 113-120
30. Comparative analysis of intracellular proteases in sporulated Bacillus thuringiensis strains.
SREELATHA T.REDDY, N.SURESH KUMAR & G.VENKATESWERLU. 1998.
Biotechnology Letters .(U.K). 20:279-281
31. Intracellular proteases in sporulated Bacillus thuringiensis subsp. kurstaki and their role in protoxin activation.
N.SURESH KUMAR & G.VENKATESWERLU. 1998.
FEMS Microbiology Letters (U.K) 166 : 377 - 382.
32. Analysis of 66kDa toxin from Bacillus thuringiensis subsp. kurstaki reveals different amino terminal processing of protoxin by endogenous protease(s).
N.SURESH KUMAR & G.VENKATESWERLU. 1998.
Biochemistry & Molecular Biology International (U.S.A), 45:769-77
33. Effect of sodium dodecyl sulfate on concanavalin-A sepharose during affinity chromatography of . high-affinity binding toxin protein of Bacillus thuringiensis subsp.kurstaki.
N.SURESH KUMAR , SREELATHA T.REDDY,& G.VENKATESWERLU. 1998.
Analytical Letters (U.K), 31:1677-1687.
34. The alkaline single cell gel electrophoresis: A new test for assessing DNA single strand breaks in Neurospora crassa.
MANJULA BHANOORI & G.VENKATESWERLU. 1998.
Mutation Research (The Netherlands), 405:29-34
35. Bacillus thuringiensis crystal d- endotoxin : Role of proteases in the conversion of protoxin to toxin
V.Rukmini , Chandrahasa Y.Reddy and G.ENKATESWERLU . 2000
Biochimie , 82 : 1 - 8 ( France )
36. Identification purification and properties of the 69 kDa intracellular protease involved in the proteolytic processing of the crystal d-endotoxin of Bacillus thuringiensis subsp.tenebrionis.
Sreelatha T.Reddy, N.Suresh Kumar and G.VENKATESWERLU. 2000
FEMS Microbiology Letters (U.K) 183 : 63 - 66
37. In vivo chitin - cadmium complexation in cell wall of Neurospora crassa.
Manjula Bhanoori and G.VENKATESWERLU , 2000
Biochemica et Biophysica Acta. 1523 : 21 - 28 ( U.S.A )
38. Intracellular proteases of Bacillus thuringiensis subsp. kurstaki and a protease
deficient mutant Btk –q.
Y.Chandrahasa Reddy & G.VENKATESWERLU, 2002
Current Microbiology (U.S.A ) 46 : 405 - 409
39. Degradation of Bacillus thuringiensis var kurstaki toxin by extracellular proteases
produced by Chrysosporium sp.
Tummala Padmaja ; Nuthakki Suneetha ; Sashidhar Rao , Beedu ; C.Sharma ;
Deshpande Vijay & G.VENKATESWERLU, 2008.
Journal of Applied Microbiology , (U.K), 104: 1171 – 1181.
40. Indian J. Botany ( In Press )
S.S.Sandhu and G.VENKATESWERLU